Telangiectatic adenoma: a variant of hepatocellular adenoma

Figure: benign, well-limited hepatocellular tumor with major haemorrhagic foci and telangiectasia on histology. Beside Focal Nodular Hyperplasia and hepatocellular adenomas, the most frequent benign hepatocellular lesion in the liver, a variant, initially called «telangiectatic focal nodular hyperplasia» now claimed as “telangiectatic adenoma” has been described recently. Initially observed in the context of vascular malformations of various organs and neoplasia of the brain, it appears that this lesion is not so rare. In a large surgical series of benign liver lesions, the previously so-called “telangiectatic focal nodular hyperplasia” accounted for approximately 15% of cases of focal nodular hyperplasia. Based on molecular evidences including clonal analysis and gene expression studies, it now clearly appears that this type of tumour belong to the group of hepatocellular adenomas. This reclassification might have some clinical relevance since such telangiectatic lesion should be aggressively managed, inthe same way that hepatocellular adenoma.